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Monday, December 02, 2013

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Listed below are links to weblogs that reference A List of 28 Studies from Around the World that Support Dr. Wakefield’s Research::

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Ross Coe

So what has this critique proven? Absolutely nothing. Its mud slinging and name calling, not science, not a debunking. Its garbage. Try again.

Facts

Do you think that it's merely a coincidence that:
that scores of studies have shown a link between autism and vaccines, it's just a coincidence that thousands and thousands of parents have witnessed immediate regression into autism after shots, it's just a coincidence that autism skyrocketed when vaccination rates skyrocketed, it's just a coincidence that 100's of millions have been paid out to autistic children in damages, and it is definitely just a coincidence that Dr Singh found significantly elevated measles antibodies in all the autistic children as compared to the normal kids in his study..??

Dorit Reiss

What this post demonstrate is that as support for the claim that vaccine cause autism, each of these studies is fundamentally flawed. None of them are credible evidence that vaccines cause autism. Since so many o them have a connection to Wakefield, no, I don't think the findings of those studies are a coincidence. Whether it's because Wakefield's confirmation bias leads him to these findings or because he's willing to do anything to clear his name by finding a connection the science disproves.

Dorit Reiss

Singh's work has been addressed above. I suggest you actually read the post. It points out why none of these studies duplicates Wakefield's opinion (we can't actually call it a finding, because his 1998 paper did not find a causal connection between MMR and autism).

Chris

Ross Coe, so nice to see you again! Perhaps you would now answer the question I quite a while ago about how Roald Dahl's experience with measles was just like autism. Come on, you can do it!

Chris

Facts: "it's just a coincidence that autism skyrocketed when vaccination rates skyrocketed,"

Well, that is interesting because Wakefield claimed it was the MMR vaccine. While three MMR vaccines were introduced in the UK in 1988, the USA had one MMR that introduced in 1971. It was the preferred vaccine for the 1978 American Measles Elimination Program. So if the MMR vaccine was a cause of autism, it would have been noticed in the 1970s and 1980s because it is a much larger country and was using it much longer than the UK.

Facts, will you please provide verifiable evidence dated before 1990 that autism increased sharply in the USA due to the MMR vaccine?

"it's just a coincidence that 100's of millions have been paid out to autistic children in damages,"

Please provide a citation, because the statistics page of the National Vaccine Injury Compensation Programs shows no such thing. Now it does show that there have been 3500 claims that have been compensated over the last twenty five years. Which is not much.

"and it is definitely just a coincidence that Dr Singh found significantly elevated measles antibodies in all the autistic children as compared to the normal kids in his study."

Actually, it is not a coincidence because he did not find those measles antibodies. Also since he was a colleague of Hugh Fudenberg, and Wakefield he would not have been independent. There seems to be a reason he left the Univ. of Utah not too long after that.

lilady

Thanks to Liz Ditz for her excellent analyses of those studies that supposedly support Andrew Wakefield's diagnosis of "MMR Vaccine-Induced Autistic Enterocolitis"

Fortunately we do have access to PubMed and by doing a search "MMR Vaccine + Autism" on PubMed we have a line listing of studies that show no association between MMR vaccine and the onset of autism:

http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=19952979

lilady

Included in that PubMed line listing of studies that find no link between MMR Vaccine and the onset of autism is this case control study:

http://www.ncbi.nlm.nih.gov/pubmed/18769550

PLoS One. 2008 Sep 4;3(9):e3140. doi: 10.1371/journal.pone.0003140.

Lack of association between measles virus vaccine and autism with enteropathy: a case-control study.

Hornig M, Briese T, Buie T, Bauman ML, Lauwers G, Siemetzki U, Hummel K, Rota PA, Bellini WJ, O'Leary JJ, Sheils O, Alden E, Pickering L, Lipkin WI.
Source

Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America. mady.hornig@columbia.edu

Abstract

BACKGROUND:

The presence of measles virus (MV) RNA in bowel tissue from children with autism spectrum disorders (ASD) and gastrointestinal (GI) disturbances was reported in 1998. Subsequent investigations found no associations between MV exposure and ASD but did not test for the presence of MV RNA in bowel or focus on children with ASD and GI disturbances. Failure to replicate the original study design may contribute to continued public concern with respect to the safety of the measles, mumps, and rubella (MMR) vaccine.

METHODOLOGY/PRINCIPAL FINDINGS:

The objective of this case-control study was to determine whether children with GI disturbances and autism are more likely than children with GI disturbances alone to have MV RNA and/or inflammation in bowel tissues and if autism and/or GI episode onset relate temporally to receipt of MMR. The sample was an age-matched group of US children undergoing clinically-indicated ileocolonoscopy. Ileal and cecal tissues from 25 children with autism and GI disturbances and 13 children with GI disturbances alone (controls) were evaluated by real-time reverse transcription (RT)-PCR for presence of MV RNA in three laboratories blinded to diagnosis, including one wherein the original findings suggesting a link between MV and ASD were reported. The temporal order of onset of GI episodes and autism relative to timing of MMR administration was examined. We found no differences between case and control groups in the presence of MV RNA in ileum and cecum. Results were consistent across the three laboratory sites. GI symptom and autism onset were unrelated to MMR timing. Eighty-eight percent of ASD cases had behavioral regression.

CONCLUSIONS/SIGNIFICANCE:

This study provides strong evidence against association of autism with persistent MV RNA in the GI tract or MMR exposure. Autism with GI disturbances is associated with elevated rates of regression in language or other skills and may represent an endophenotype distinct from other ASD.

CrackerJack Nurse

Doctors like to speak of the inability to convince some one with "empirical knowledge" to be convince he is wrong with studies and statistics. For instance, if the doctor gave prednisone to a patient with a migraine and the migraine went away, it is almost impossible to convince that doc that prednisone is useless for the treatment of migraine regardless of any studies that might say otherwise.
"Empirical knowledge" is our own experience and we learn from our experiences. I wouldn't argue about vaccines....I would simply avoid them and spend my energy protecting the personal rights that allow me to refuse to be vaccinated.

lilady

Cracker Jack Nurse:

Which vaccine(s) have you refused?

Which health care facility permits you to work and to not be vaccinated (or alternatively, show serological proof of immunity) against vaccine-preventable-diseases)?

Have you gotten your Tdap booster vaccine...or does the health care facility where you are employed give you "a pass"...based on your empirical knowledge?

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